DIACORDON® ELISA

 

   DIACORDON® ELISA
  Know your Heart

 

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DIACORDON® ELISA is a blood test for the early detection of an acute myocardial infarction. It works on an enzyme basis and can detect Glycogen-Phosphorylase Isoenzyme BB (GPBB) via antibodies owned by Diagenics Group. The enzyme GPBB enters the bloodstream as soon as a myocardial ischemia occurs. In the long run, such an insufficient oxygen supply leads to a necrosis (death) of the affected cells and thereby to an infarction. Moreover, the detection of GPBB in the blood provides information about the progress of the coronary syndrome (including unstable angina pectoris) and classic cases of heart attack. That way it contributes decisively to the early diagnosis of heart infarction patients. There are already markers, such as myoglobin and troponin, which contribute to the diagnosis and are routinely applied in cases of a myocardial infarction. Myoglobin, however, has the disadvantage of not being heart specific. It can also be detected after damages of the skeletal muscles or after acute renal failure and thus does not give a clear answer. Troponin, on the other hand, is heart specific, but can only be detected three to six hours after the first symptoms (chest pain). And since Troponin is a necrosis marker, it can only be detected after heart cells have already suffered irreversible damage. GPBB is not only heart specific but also early detectable, i.e. within the first hour after symptoms start. In case of acute coronary syndromes this is a vital advantage, since a quick and exact diagnosis can save many lives.



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